Cell BiologyScientific ReportsPeer-reviewed
Coherent Raman microscopy detects nucleolar defects through amide I peak shifts originating from β-sheets: an application to visualizing ongoing cellular senescence
Shigeo Ishibashi, Akihito Inoko, Yuki Oka…·Hideaki Kano
This paper introduces a label-free method using coherent Raman microscopy to detect nucleolar defects associated with cellular senescence by analyzing amide I peak shifts in nucleoli.