High-throughput TCRB enrichment sequencing of human cord blood exhibited a distinct fetal T cell repertoire in the third trimester of pregnancy
Yan Dong, Wei Chen, Jinmin Wang…·Yuan Wei
This study analyzes the TCRB repertoire in human cord blood from 24-38 weeks gestation, finding fetal TCRB repertoires have lower diversity and shorter CDR3s compared to adults, with CDR3 length increasing with gestational age.