Johannes Jaeger

Modularity, criticality and evolvability of a developmental gene regulatory network

The paper shows that a developmental gene regulatory network, though not structurally modular, exhibits dynamical modules with different evolvability due to criticality states.

tarsal-less is expressed as a gap gene but has no gap gene phenotype in the moth midge Clogmia albipunctata.

The paper shows that tarsal-less (Ca-tal) in Clogmia albipunctata is expressed and regulated like a gap gene but does not function as one, lacking a gap gene phenotype.

Two consecutive microtubule-based epithelial seaming events mediate dorsal closure in the scuttle fly Megaselia abdita

The paper shows that dorsal closure in Megaselia abdita uses two microtubule-based seaming events instead of the single event in Drosophila, highlighting a morphogenetic evolution without changing signaling pathways.

A damped oscillator imposes temporal order on posterior gap gene expression in Drosophila

The paper shows that a damped oscillator mechanism drives posterior gap gene expression shifts in Drosophila, suggesting similarities between long- and short-germband segmentation.

Dynamic Maternal Gradients Control Timing and Shift-Rates for Gap Gene Expression

The paper shows maternal morphogen decay controls timing and rate of gap gene expression in Drosophila embryos through dynamic regulatory effects.

Gap gene regulatory dynamics evolve along a genotype network

The paper models gap gene regulatory dynamics in two dipteran species to show how compensatory mechanisms produce similar developmental outcomes despite differences in gene expression.