Linus Butt

This study identifies MAGI2 as a conserved biomarker for podocyte injury, showing its downregulation in glomerular diseases and differential expression in primary vs secondary FSGS.

The paper develops single-cell damage scores to quantify cellular deterioration in degenerative diseases and applies them to murine and human datasets to identify molecular trajectories of damage.

This paper introduces a fast and simple optical clearing and swelling protocol for 3D visualization of kidney ultrastructure using conventional confocal microscopy.

This paper introduces an optimized electroporation method for CRISPR/Cas9 genome editing in murine zygotes, achieving 100% successful genome editing with reduced embryo damage.

The paper develops a method to analyze individual nephron proteomes in kidney disease, identifying lysosomal protein overexpression as a key mechanism in proteinuric diseases.