James C. McPartland

Synaptic density imaging associates with performance but not self-report in autism

The paper examines the relationship between synaptic density imaging and performance versus self-report measures in autism, finding a dissociation where synaptic density correlates with performance but not self-report.

Heterogeneity of Brain Dynamics in Genetic and Psychiatric Conditions

The paper analyzes EEG data from 4,812 individuals to identify shared and distinct neurophysiological signatures across psychiatric conditions and rare genetic variants.

Rare variation illuminates the distinct and pleiotropic genetic architecture of autism across neuropsychiatric traits

The paper identifies 253 autism-associated genes using rare variation from 62,429 individuals and finds pleiotropy across physiological systems and developmental disorders.

Altered aperiodic EEG spectral power during speech perception task is associated with verbal communication in youths with Autism Spectrum Disorder

The paper investigates altered aperiodic EEG spectral power during speech perception in youths with ASD, linking increased neural noise to lower verbal communication skills.

Structural Determinants of Signal Speed: A Multimodal Investigation of Face Processing in Autism Spectrum Disorder

The paper introduces a novel metric, estimated axonal latency, to measure neuronal processing speed in autism spectrum disorder using MRI and EEG data.

Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD Suggest Age Mediates Subtypes of ASD

This study identifies widespread associations between behavioral metrics and brain microstructure in ASD, suggesting age-related changes may drive different behavioral subtypes.

Conduction Velocity, G-ratio, and Extracellular Water as Microstructural Characteristics of Autism Spectrum Disorder

This study uses MRI metrics to identify microstructural differences in myelin and axons between ASD and neurotypical adolescents, finding increased extracellular water and decreased g-ratio and conduction velocity.

Enhancer-driven regulatory network of forebrain human development provides insights into autism

The paper constructs an enhancer-driven gene regulatory network from human forebrain organoids with ASD and neurotypical controls, identifying key regulators of excitatory neuron specification in macrocephalic ASD.

ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

The paper models ASD in organoids and finds transcriptomic imbalances in excitatory cortical neuron subtypes during early neurogenesis in ASD probands.

Within Visit Test-Retest Reliability of EEG Profiles in Children with Autism Spectrum Disorder and Typical Development

The paper assesses the test-retest reliability of EEG PSD profiles in children with ASD and TD controls using two analytical approaches, showing stable individual signatures across sessions.

Implementation of a pre- and in-scan system to minimize head motion in pediatric participants undergoing fMRI scans

The paper describes a pre- and in-scan system to reduce head motion in pediatric fMRI scans, showing improved motion control with formal mock scans.