Molecular BiologybioRxivPreprint
Invigorating human MSCs for transplantation therapy via Nrf2/DKK1 co- stimulation in a mice acute-on-chronic liver failure model
Feng Chen, Zhaodi Che, Yingxia Liu…·Jia Xiao
This study shows that co-stimulating Nrf2 and DKK1 in human MSCs improves their therapeutic efficacy in a mouse ACLF model by enhancing anti-inflammatory and regenerative effects.
DOI 10.1101/2022.05.29.493908