Sonia Corbett Karkare

Projection populations form a dorsoventral gradient of reward representations in the lateral septum

The paper identifies two distinct projection populations in the lateral septum with opposing reward responses and shows their role in reward-seeking behavior.

Comparative gene editing reduces dopamine receptor levels across rodent species

This paper develops a CRISPR/Cas9-based method to reduce dopamine receptor levels in multiple rodent species, enabling comparative studies of neural mechanisms.

Organization of brainwide inputs to discrete lateral septum projection populations

This study maps brainwide inputs to six discrete lateral septum projection populations, revealing unique region-dependent innervation patterns.

A ventral hippocampal-lateral septum pathway regulates social novelty preference.

This study identifies a vHPC-LS-VTA pathway necessary for mice to preferentially investigate novel conspecifics using chemogenetics, optogenetics, and monosynaptic rabies tracing.

Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex.

The paper identifies sex-dependent, non-overlapping neural representations of social and nonsocial reward in the medial prefrontal cortex that vary with internal state and are essential for reward-seeking behavior.