Jennifer Isaac

The paper identifies two distinct projection populations in the lateral septum with opposing reward responses and shows their role in reward-seeking behavior.

The paper shows that BLA neurons in mice encode social and food rewards distinctly, with differences in response bias and sensitivity to reward omissions compared to mPFC.

This study maps brainwide inputs to six discrete lateral septum projection populations, revealing unique region-dependent innervation patterns.

This study identifies a vHPC-LS-VTA pathway necessary for mice to preferentially investigate novel conspecifics using chemogenetics, optogenetics, and monosynaptic rabies tracing.

The paper identifies sex-dependent, non-overlapping neural representations of social and nonsocial reward in the medial prefrontal cortex that vary with internal state and are essential for reward-seeking behavior.