Matthieu X. Moreau

Bidirectional interaction between Protocadherin 8 and transcription factor Dbx1 regulates cerebral cortex development

The paper shows that Protocadherin 8 and Dbx1 interact bidirectionally to regulate cerebral cortex development through changes in neuronal identity and polarity.

Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis

The paper investigates the role of P73+ Cajal-Retzius cells and Reelin in cortical morphogenesis, finding that CRs-derived Reelin is essential for radial migration arrest, while CRs also have Reelin-independent functions in hippocampal progenitor proliferation and vessel remodelling.

Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons

The paper identifies a gene regulatory network involved in multiciliation that is repurposed in the fate specification of Cajal-Retzius neurons, leading to distinct cellular outcomes.

Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages

The paper shows Dbx1-expressing progenitors in the olfactory epithelium contribute to multiple neuronal lineages, revealing unexpected diversity in their neurogenic potential.

Single-cell transcriptomics of the early developing mouse cerebral cortex disentangles the spatial and temporal components of neuronal fate acquisition

This study uses single-cell RNAseq to analyze progenitor and neuronal diversity in the developing mouse cerebral cortex, revealing how spatial and temporal factors contribute to neuronal fate acquisition.