NeuroscienceNeurobiology of StressPeer-reviewed
Rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK) targets glucocorticoid receptor signaling: a longitudinal cerebrospinal fluid proteome study
David P. Herzog, Natarajan Perumal, Caroline Manicam…·Marianne B. Müller
This study identifies HNK's mechanism of action by analyzing CSF proteome changes, showing its impact on glucocorticoid receptor signaling and potential upstream regulators.
19 citations