Author
Washington University in St. LouisORCID 0000-0002-2623-0547Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Caitlin B. Dingwall, Yo Sasaki, Amy M. Strickland…·Jeffrey Milbrandt
The paper shows that overexpressing ABHD12 in neurons reduces macrophage activation and preserves axon integrity in a sarmopathy model by modulating phosphatidylserine levels.
Caitlin B. Dingwall, Amy M. Strickland, Sabrina W. Yum…·Jeffrey Milbrandt
This study shows that macrophage depletion reverses neuropathic symptoms in a mouse model of SARM1-dependent neuropathy caused by NMNAT2 variants.
Tong Wu, Jian Zhu, Amy M. Strickland…·Jeffrey Milbrandt
This study identifies neurotoxins that activate SARM1 by binding to its allosteric site, leading to NAD+ depletion and neuronal death.