Author

James M. Hoffman

St. Jude Children's Research HospitalORCID 0000-0002-2625-7766Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aditya H. GauriD· 1 shared Allison M. KirkiD· 1 shared Amanda ColeiD· 1 shared Anastasia A. MinervinaiD· 1 shared Ashleigh GoweniD· 1 shared Ashley H. CastellawiD· 1 shared Balaji SundararamaniD· 1 shared Brandi L. Clark· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aditya H. GaurORCID

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1 paper

Recent·Most cited

ImmunologyNature MethodsPeer-reviewedNov 24, 2025

TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing

Mikhail V. Pogorelyy, Allison M. Kirk, Samir Adhikari…·Paul Glyndwr Thomas

TIRTL-seq provides a scalable, cost-effective method for paired TCR repertoire sequencing, enabling accurate identification of TCR chain pairings and clonotype dynamics in large cohorts.

43 citationstop 1%

humanscRNA-seq

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