Author

Mikhail V. Pogorelyy

St. Jude Children's Research HospitalORCID 0000-0003-0773-1204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:scRNA-seq· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Anastasia A. MinervinaiD· 4 shared Paul Glyndwr ThomasiD· 3 shared Aleksandra M. WalczakiD· 2 shared Kasi VegesanaiD· 2 shared Thierry MoraiD· 2 shared Aditya H. GauriD· 1 shared Allison M. KirkiD· 1 shared Amanda ColeiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

Anastasia A. MinervinaORCID

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4 papers

Recent·Most cited

ImmunologyPLoS Computational BiologyPeer-reviewedJan 16, 2026

TCR2HLA: calibrated inference of HLA genotypes from TCR repertoires enables identification of immunologically relevant metaclonotypes

Koshlan Mayer-Blackwell, Anastasia A. Minervina, Mikhail V. Pogorelyy…·Andrew J. Fiore-Gartland

TCR2HLA infers HLA genotypes from TCR repertoires, enabling identification of immunologically relevant metaclonotypes and discovery of HLA-associated TCRs.

3 citationstop 5%

humanscRNA-seq

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ImmunologyNature MethodsPeer-reviewedNov 24, 2025

TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing

Mikhail V. Pogorelyy, Allison M. Kirk, Samir Adhikari…·Paul Glyndwr Thomas

TIRTL-seq provides a scalable, cost-effective method for paired TCR repertoire sequencing, enabling accurate identification of TCR chain pairings and clonotype dynamics in large cohorts.

43 citationstop 1%

humanscRNA-seq

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ImmunologyPLoS Computational BiologyPeer-reviewedJan 6, 2025

Learning predictive signatures of HLA type from T-cell repertoires

María Ruiz Ortega, Mikhail V. Pogorelyy, Anastasia A. Minervina…·Thierry Mora

The paper develops a model to predict HLA types from TCR repertoires using associations inferred from HLA-typed donors.

29 citationstop 3%

humanscRNA-seq

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GeneticsPLoS GeneticsPeer-reviewedJan 4, 2021

Immune Fingerprinting through Repertoire Similarity

Thomas Dupic, Meriem Bensouda Koraichi, Anastasia A. Minervina…·Aleksandra M. Walczak

This study demonstrates that immune repertoires can uniquely identify individuals with high accuracy using a classifier based on repertoire similarity.

18 citations

humanCITE-seq

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