ImmunologybioRxivPreprint
Immune Checkpoint Therapy Drives Maturation of a Cellular Neighborhood Nucleated by T Cell-APC Triads Enabling Spatially Compartmentalized Tumor Immunity
Ruan F.V. Medrano, Vladimir Sukhov, Kevin Hoffer-Hawlik…·Robert D. Schreiber
The paper uses multiplex imaging to track the development of T cell-APC triad neighborhoods during immune checkpoint therapy, showing their role in spatially organizing tumor immunity.