Dual Recognition Drives Site-Directed G-Quadruplex Stabilization: Exploring Oligonucleotide Design in G4 Ligand-Oligonucleotide Conjugates
Alva Abrahamsson, Sakina Khwaja, Namrata Chaudhari, Steven Vertueux, Andreas Berner, Koit Aasumets, Chandan Kumar, Lotte Stietz, Tom Baladi, Anders Dahlén, Sjoerd Wanrooij, Erik Chorell
This study explores how oligonucleotide design affects G4 ligand-conjugated oligonucleotide binding and stabilization of G-quadruplex structures.
Molecular Therapy — Nucleic Acids · Aug 14, 2026Peer-reviewedMolecular Biology