Dandy Walker-like malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development
Sara Gillnäs, Radiosa Gallini, Liqun He, Christer Betsholtz, Johanna Andræ
The paper shows that PDGF-C/PDGFRα signaling is critical for cerebellar development, as its loss in mice causes hypoplasia, malformation, and ependymal denudation.
bioRxiv · May 13, 2022 · PreprintDevelopmental Biology