Liqun He

The paper examines immune suppressive gene expression in normalized breast cancer endothelial cells and finds similarities with healthy human endothelial cells.

The paper identifies artery-like smooth muscle cells in dural venous sinuses that actively regulate venous outflow through contractile function and calcium signaling.

The paper creates a molecular atlas of mouse liver cell types using single-cell RNA sequencing, revealing new insights into hepatic endothelial and mesenchymal cells and their responses to fibrosis.

This study identifies cellular and molecular mechanisms of tertiary lymphoid structure (TLS) formation in glioblastoma, showing TLS correlate with improved survival and are driven by CD4 T cells expressing lymphotoxin β.

This study shows that endothelial tip cells use hydrostatic pressure and actin polymerization to migrate and sprout blood vessels, with Aqp1a.1 and Aqp8a.1 playing a key role in this process.

The paper shows that PDGF-C/PDGFRα signaling is critical for cerebellar development, as its loss in mice causes hypoplasia, malformation, and ependymal denudation.

This study identifies Akt's role in dorsal aorta formation by showing it sustains arterial progenitor specification and segregation in zebrafish.

The paper characterizes S1PR1-regulated transcriptomes in aortic endothelial cells, revealing distinct subtypes and signaling mechanisms in arterial and lymphatic endothelium.