Stuart M. Grieve

Single-cell eQTL mapping in 5.4 million PBMCs from 1,925 individuals with matched WGS finds common-variant eQTLs for 83% and rare-variant signals for 47% of 21,404 genes.

The paper identifies immune cell type-specific gene expression regulated by tandem repeats using multi-omics data from large cohorts.

This study identifies CCBE1 as a gene associated with mitochondrial dysfunction in atherosclerosis using transcriptomic analysis of endothelial cells from CAD patients.

This study examines functional connectivity changes in the Default Mode Network of Australian Rules Football players using resting-state fMRI to assess potential as an early biomarker for non-concussive impacts.

This paper develops zero-inflated regression models to better analyze Coronary Artery Calcium Scores by addressing the high prevalence of zeros in the data.

The paper develops a framework to construct multi-platform precision diagnostic pathways automatically, optimizing for accuracy and cost-effectiveness in clinical settings.

The paper introduces hRUV, a hierarchical method to remove unwanted variation in large-scale metabolomics data, showing improved preservation of biological signals.