NeurosciencebioRxivPreprint
SBT-272 improves TDP-43 pathology in the ALS motor cortex by modulating mitochondrial integrity, motility, and function
Mukesh Gautam, Barış Genç, Benjamin Helmold…·P. Hande Özdi̇nler
This study shows that SBT-272 improves mitochondrial structure, motility, and function in TDP-43 pathology of ALS motor neurons, reducing inflammation and preserving neuron health.
DOI 10.1101/2022.10.04.510854