Kevin Zhu

This study evaluates ULI-HiFi and dMDA for long-read sequencing of low-input samples, finding ULI-HiFi achieves higher variant detection accuracy and reveals disease-relevant genetic changes in a FAP patient.

The paper identifies recurrent repeat expansions in cancer genomes, showing their association with gene regulation and demonstrating their therapeutic targeting potential.

The paper uses deep RNA sequencing to compare gene expression in the subgenual anterior cingulate cortex across major psychiatric disorders and controls, finding disorder-specific expression changes and genetic associations.