Erika M. Kvikstad

This study uses proteome-wide Mendelian randomization to identify 221 candidate causal proteins and 16 biomarkers for cardiovascular diseases, distinguishing between direct causes and consequences of CVD.

The paper maps genetic associations with plasma proteins in 54,306 UK Biobank participants, identifying 10,248 new protein quantitative trait loci (pQTLs) and expanding the genetic architecture of the plasma proteome.

The paper describes exome sequencing of 200,643 UK Biobank participants, providing a rich resource of coding variants for genetic and drug discovery research.

This paper introduces TE-NGS, a targeted sequencing protocol and computational pipeline to identify polymorphic and novel transposable element insertions in human genomes, demonstrating high sensitivity and precision.