Matthew Traylor

The paper identifies tissue-specific protein regulation and pQTLs associated with cardiometabolic disease using multi-tissue proteomic data from STARNET patients.

The paper maps genetic associations with plasma proteins in 54,306 UK Biobank participants, identifying 10,248 new protein quantitative trait loci (pQTLs) and expanding the genetic architecture of the plasma proteome.

This study conducts a trans-ancestry GWAS of rheumatoid arthritis, identifying 124 loci, 34 novel, and shows improved polygenic risk score performance across populations.

This paper uses genetic data to support cardiorespiratory fitness (CRF) as a clinical vital sign and advocates for routine physical activity prescription in healthcare.

This study uses Mendelian randomization to identify plasma proteins associated with stroke risk and potential therapeutic targets.

The paper identifies rare variants in HTRA1 and its substrate EGFL8 associated with increased white matter hyperintensities using whole-exome sequencing data from 16,511 UK Biobank individuals.

The paper identifies subtype-specific genetic loci associated with stroke subtypes and finds heterogeneity in their effects across different stroke types.

This study investigates genetic associations between major depression and cardio-metabolic traits, finding shared genetic aetiology regardless of depression onset age.

This study evaluates the clinical relevance of pharmacogenetic tests offered by 23andMe, finding variability in validity and utility across tests and populations.