NeurosciencePLoS Computational BiologyPeer-reviewed
Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals
Neil J. Bruce, Daniele Narzi, Daniel Trpevski…·Jeanette Hellgren Kotaleski
The paper uses simulations to show that the inactive ternary complex of AC5, Golf, and Gi enables synergistic cAMP production in response to coincident neuromodulatory signals.
26 citations