Anu G. Nair

Distinct molecular pathways govern presynaptic homeostatic plasticity

The paper shows that different receptor perturbations leading to reduced synaptic activity trigger distinct molecular pathways for presynaptic homeostatic plasticity in Drosophila.

A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience

The paper introduces a modular workflow for building, analyzing, and parameter estimating biochemical models, enhancing interoperability and reusability across different simulators and formats.

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

The paper uses simulations to show that the inactive ternary complex of AC5, Golf, and Gi enables synergistic cAMP production in response to coincident neuromodulatory signals.

Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models

The paper combines Bayesian analysis and global sensitivity analysis to quantify and propagate uncertainty in dynamical intracellular pathway models, identifying key parameters for experimental focus.