Author

Alexandra M. Dumitrescu

University of ChicagoORCID 0000-0002-2743-770XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Brian K. KaspariD· 1 shared Catherine J. BreseeiD· 1 shared Clive Niels SvendseniD· 1 shared Gad David VatineiD· 1 shared Heike HeueriD· 1 shared Jean‐Philippe VitiD· 1 shared Kathrin MeyeriD· 1 shared Michael ShiloiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Brian K. KasparORCID

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1 paper

Recent·Most cited

AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in an AHDS mouse model

Xiao-Hui Liao, Pablo Avalos, Oksana Shelest, Raz Ofan, Michael Shilo, Catherine J. Bresee, Shibi B. Likhite, Jean‐Philippe Vit, Heike Heuer, Brian K. Kaspar, Kathrin Meyer, Alexandra M. Dumitrescu, Samuel Refetoff, Clive Niels Svendsen, Gad David Vatine

This study shows that juvenile AAV9-MCT8 gene therapy improves neurological and behavioral deficits in an AHDS mouse model by restoring TH levels and gene expression.

bioRxiv · Oct 31, 2021 · PreprintNeuroscience