Author

Laura D. Mathies

Virginia Commonwealth UniversityORCID 0000-0002-2749-6531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Evan M. SoukupiD· 2 shared Jill C. BettingeriD· 2 shared Alan’da E. Thomas· 1 shared Andrew C. KimiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersDevelopmental Biology

Evan M. SoukupORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintOct 16, 2023

PBRM-1/PBAF-regulated genes in a multipotent progenitor

Laura D. Mathies, Andrew C. Kim, Evan M. Soukup…·Jill C. Bettinger

The paper identifies PBRM-1/PBAF-regulated genes in C. elegans mesodermal cells, showing PBAF promotes muscle differentiation and regulates SGP/hmc fate decisions.

DOI 10.1101/2023.10.16.562537

C. elegansbulk RNA-seq

GeneticsG3 Genes Genomes GeneticsPeer-reviewedSep 5, 2022

Transcription factors regulating the fate and developmental potential of a multipotent progenitor in C. elegans

Evan M. Soukup, Jill C. Bettinger, Laura D. Mathies

The paper identifies transcription factors regulating the fate and developmental potential of C. elegans somatic gonadal progenitors through genetic screening and functional analysis.

4 citations

C. elegansexperimental assay