The paper identifies PBRM-1/PBAF-regulated genes in C. elegans mesodermal cells, showing PBAF promotes muscle differentiation and regulates SGP/hmc fate decisions.

bioRxiv · Oct 16, 2023 · PreprintDevelopmental Biology

Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach

Amanda Elswick Gentry, Jeffry C. Alexander, Mohammad Mehdi Ahangari, Roseann Elizabeth Peterson, Michael F. Miles, Jill C. Bettinger, Andrew G. Davies, Mike Groteweil, Silviu‐Alin Bacanu, Kenneth S. Kendler, Brien P. Riley, Bradley Todd Webb

The paper analyzes rare functional variation in genes related to ethanol metabolism in severe alcohol dependence cases using a case-only design and WES data from the island of Ireland.

PLoS ONE · Apr 25, 2023Peer-reviewedGenetics

Transcription factors regulating the fate and developmental potential of a multipotent progenitor in C. elegans

Evan M. Soukup, Jill C. Bettinger, Laura D. Mathies

The paper identifies transcription factors regulating the fate and developmental potential of C. elegans somatic gonadal progenitors through genetic screening and functional analysis.

G3 Genes Genomes Genetics · Sep 5, 2022Peer-reviewedGenetics