Author

Patrick J. Feehley

Johns Hopkins UniversityORCID 0000-0002-2749-9601Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

Gregory P. ContrerasiD· 3 shared Michael C. FeehleyiD· 3 shared Ting‐Yu YehiD· 3 shared Vivian Y. Ooi· 2 shared Chia-En Hong· 1 shared Feng-Yu Kuo· 1 shared Frederick Hsieh· 1 shared Maxwell S. Lewis· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Gregory P. ContrerasORCID

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3 papers

Recent·Most cited

Recombination alters the receptor binding and furin cleavage site in novel bat-borne HKU5-CoV-2 coronavirus

Ting‐Yu Yeh, Vincent Tsai, Samuel M. Liao, Chia-En Hong, Feng-Yu Kuo, Yen Chun Wang, Michael C. Feehley, Patrick J. Feehley, Yi-Chen Lai, Gregory P. Contreras

This study identifies recombination events in HKU5-CoV-2 that affect the spike protein's receptor binding domain and furin cleavage site, potentially altering host tropism and infectivity.

Microbiology Spectrum · Aug 29, 2025Peer-reviewedMicrobiology

The packaging signal of Xanthomonas integrative filamentous phages

Ting‐Yu Yeh, Patrick J. Feehley, Michael C. Feehley, Vivian Y. Ooi, Pei‐Chen Wu, Frederick Hsieh, Serena S. Chiu, Yung-Ching Su, Maxwell S. Lewis, Gregory P. Contreras

The paper identifies and characterizes the packaging signal of two Xanthomonas integrative filamentous phages, revealing structural and functional insights into their assembly mechanism.

Virology · Oct 30, 2024Peer-reviewedMolecular Biology

A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages

Ting‐Yu Yeh, Michael C. Feehley, Patrick J. Feehley, Vivian Y. Ooi, Yi-Yung Hung, Shao-Cheng Wang, Gregory P. Contreras

The paper identifies PSB15 as a protein essential for integrative filamentous phage assembly, showing it binds packaging signals and interacts with host proteins to regulate the assembly checkpoint.

bioRxiv · Mar 19, 2024 · PreprintMicrobiology