NeurosciencebioRxivPreprint
Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
Christoffer G. Alexandersen, Julia K. Brynildsen, Alice Prigent…·Dani S. Bassett
The paper analyzes longitudinal histopathology data to show that α-synuclein pathology follows rise-and-fall dynamics, revealing a vulnerability axis linked to energy metabolism and monoaminergic neurons.
DOI 10.64898/2026.03.27.714785