Julia K. Brynildsen

Longitudinal changes in control energy of brain networks in older adults at familial risk for Alzheimers disease

This study examines how control energy in brain networks changes over time in older adults at risk for Alzheimer's disease, finding specific patterns linked to cognitive performance and biomarkers.

Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation

The paper analyzes longitudinal histopathology data to show that α-synuclein pathology follows rise-and-fall dynamics, revealing a vulnerability axis linked to energy metabolism and monoaminergic neurons.

Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability

The paper identifies group II p21-activated kinases as regulators of α-synucleinopathy by linking network vulnerability analysis to gene expression and pharmacological interventions.

LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread

This study shows that LRRK2 kinase inhibition reverses tau pathology progression in mice with the G2019S mutation but not in wildtype mice.

Using network control theory to study the dynamics of the structural connectome

This paper introduces a framework for applying network control theory to the human structural connectome to study neural dynamics and control energy, controllability, and their correlations with behavior and mental health.

An open, analysis-ready, and quality controlled resource for pediatric brain white-matter research

The paper curates and provides analysis-ready diffusion MRI data for pediatric brain white-matter research, including automated quality control using a trained neural network.