Author

Roseanna N. Zia

Stanford UniversityORCID 0000-0002-2763-9811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:E. coli· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Approach:simulation· 1

Frequent Co-Authors

Alp M. SunoliD· 1 shared Benjamin P. BrattoniD· 1 shared Diana Valverde-MendeziD· 1 shared Gesse A. RoureiD· 1 shared Jennifer L. HofmanniD· 1 shared Joseph P. SheehaniD· 1 shared Joshua W. ShaevitziD· 1 shared Liam J. HoltiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

Alp M. SunolORCID

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2 papers

Recent·Most cited

BiophysicsPLoS Computational BiologyPeer-reviewedJan 27, 2026

Abundant positively-charged proteins underlie JCVI-Syn3A's expanded nucleoid and ribosome distribution

Gesse A. Roure, Vishal Sankar Sivasankar, Roseanna N. Zia

The paper develops a computational model of JCVI-Syn3A to explain its expanded nucleoid and ribosome distribution, finding that positively-charged proteins enable ribosome interpenetration.

1 citation

deep learningstatistical model

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJan 24, 2025

Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells

Diana Valverde-Mendez, Alp M. Sunol, Benjamin P. Bratton…·Roseanna N. Zia

This study tracks ribosome-sized particles in E. coli to show that their 3D diffusion is influenced by macromolecular interactions and geometrical confinement, revealing sub-diffusive motion due to nucleoid and cell boundary constraints.

23 citationstop 1%

E. colifluorescence / live-cell microscopy

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