Statin-dye conjugates for selective targeting of KRAS mutant cancer cells
Hye‐ran Moon, Zhenying Cai, Bo Kyung Cho, Hyeyoun Chang, Seung Taek Hong, Jean J. Zhao, Ick Chan Kwon, Thomas M. Roberts, Bumsoo Han, Ju Hee Ryu
The paper demonstrates that statin-dye conjugates are selectively taken up by KRAS mutant cancer cells through enhanced macropinocytosis, enabling targeted killing of these cells without affecting KRAS wild-type cells.
PLoS ONE · Jan 9, 2026Peer-reviewedCancer Biology