Author

Hye‐ran Moon

Purdue University West LafayetteORCID 0000-0001-7456-6398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Bumsoo HaniD· 2 shared Abigail D. CoxiD· 1 shared Bennett D. ElzeyiD· 1 shared Bo Kyung Cho· 1 shared Claudius H. ConradiD· 1 shared Duy DoiD· 1 shared Hyeyoun ChangiD· 1 shared Ick Chan KwoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Bumsoo HanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

Extravascular coagulation stabilizes pro-fibrotic stromal states via tumor-intrinsic PAR1 signaling in pancreatic ductal adenocarcinoma

Sae Rome Choi, Natalia Ospina-Muñoz, Hye‐ran Moon…·Bumsoo Han

This study identifies extravascular coagulation as a regulator of fibrotic stromal states in PDAC via tumor-intrinsic PAR1 signaling, showing PAR1 inhibition can reprogram the tumor-promoting stroma.

DOI 10.64898/2026.06.25.734662

humanbulk RNA-seq

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Cancer BiologyPLoS ONEPeer-reviewedJan 9, 2026

Statin-dye conjugates for selective targeting of KRAS mutant cancer cells

Hye‐ran Moon, Zhenying Cai, Bo Kyung Cho…·Ju Hee Ryu

The paper demonstrates that statin-dye conjugates are selectively taken up by KRAS mutant cancer cells through enhanced macropinocytosis, enabling targeted killing of these cells without affecting KRAS wild-type cells.

1 citation

humanproteomics

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