Mark N. Ragheb

Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those with structured RNAs

This study identifies Mfd's role in regulating RNAP association at hard-to-transcribe regions, particularly those with structured RNAs, and shows its importance in transcription regulation and evolution.

Head-on replication-transcription collisions lead to formation of life threatening R-loops

The paper shows that head-on replication-transcription conflicts in Bacillus subtilis lead to R-loop formation, which halts replication and gene expression, and is critical for stress survival.