Author

Christopher N. Merrikh

University of WashingtonORCID 0000-0001-5017-6037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Houra MerrikhiD· 2 shared Mark N. RaghebiD· 2 shared Ashley N. HalliD· 1 shared Kaitlyn R. BrowningiD· 1 shared Kevin S. LangiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersMolecular Biology

Houra MerrikhORCID

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2 papers

Recent·Most cited

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedDec 21, 2020

Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those with structured RNAs

Mark N. Ragheb, Christopher N. Merrikh, Kaitlyn R. Browning, Houra Merrikh

This study identifies Mfd's role in regulating RNAP association at hard-to-transcribe regions, particularly those with structured RNAs, and shows its importance in transcription regulation and evolution.

27 citations

bacteria (other)DNA methylation

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Molecular BiologybioRxivPreprintJun 23, 2017

Head-on replication-transcription collisions lead to formation of life threatening R-loops

Kevin S. Lang, Ashley N. Hall, Christopher N. Merrikh…·Houra Merrikh

The paper shows that head-on replication-transcription conflicts in Bacillus subtilis lead to R-loop formation, which halts replication and gene expression, and is critical for stress survival.

1 citation

bacteria (other)DNA methylation

𝕏 PostBluesky