Author

Kevin S. Lang

University of MinnesotaORCID 0000-0002-7856-7459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Houra MerrikhiD· 2 shared Ashley N. HalliD· 1 shared Christopher N. MerrikhiD· 1 shared Madison Ahmed· 1 shared Mark N. RaghebiD· 1 shared Rodney TollersoniD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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2 shared papersMolecular Biology

Houra MerrikhORCID

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3 papers

Recent·Most cited

Translation elongation factor EF-P drives susceptibility to fluoroquinolone antibiotics in Bacillus subtilis

Madison Ahmed, Rodney Tollerson, Kevin S. Lang

This study shows that loss of EF-P increases survival of Bacillus subtilis to fluoroquinolones, highlighting EF-P's role in susceptibility through post-translational modification and interaction with DNA repair pathways.

bioRxiv · Sep 28, 2026 · PreprintMicrobiology

Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts

Kevin S. Lang, Houra Merrikh

The paper identifies topological stress as the cause of more severe outcomes in head-on replication-transcription conflicts compared to co-directional conflicts.

Cell Reports · Mar 1, 2021Peer-reviewedMolecular Biology

Head-on replication-transcription collisions lead to formation of life threatening R-loops

Kevin S. Lang, Ashley N. Hall, Christopher N. Merrikh, Mark N. Ragheb, Houra Merrikh

The paper shows that head-on replication-transcription conflicts in Bacillus subtilis lead to R-loop formation, which halts replication and gene expression, and is critical for stress survival.

bioRxiv · Jun 23, 2017 · PreprintMolecular Biology