Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
Andrew J. Ingersoll, Devlon M. McCloud, Jane G. Hu, Michael Rapé
This study identifies TRIP12 as a key regulator of NRF2 degradation during oxidative stress recovery, showing it accelerates stress response silencing but limits NRF2 activation.
Cell Reports · Sep 1, 2025Peer-reviewedBiochemistry