Sunil Puria

Sound-Driven Motion of Human Cochlear Structures Depends on Organ of Corti Integrity

This study uses OCT to show that the anatomical integrity of the organ of Corti affects cochlear structural motion in human cadaveric specimens.

A nonlinear time-domain finite-element model of the human middle ear subjected to intense sound waves

This study develops a nonlinear finite-element model of the human middle ear to simulate its response to intense sound waves and identifies nonlinear behaviors under high-frequency and high-intensity conditions.

Sound from Ultrasound: Characterization of a MEMS-based personal-audio device in human temporal bones

This study characterizes ultrasonic acoustic output from a MEMS-based audio device in human temporal bones, measuring sound pressure levels and vibration velocities to assess biological exposure.

Anatomical integrity of the human cochlea estimated with optical coherence tomography for future clinical application

This paper uses OCT to image fresh human cochleae non-invasively, identifying structural variations and developing a cochlear integrity rating system for potential clinical diagnostics.

From Simulations to Inference: Using Machine Learning to Tune Patient-Specific Finite-Element Models of the Middle Ear Towards Objective Diagnosis

This paper uses simulation-based inference to tune a finite-element model of the middle ear, providing probability distributions of parameters that reproduce experimental data and enabling objective diagnosis of hearing loss.

Computational model of the human cochlea with motion of the layered osseous spiral lamina

The paper develops a finite element model of the human cochlea incorporating the layered osseous spiral lamina, calibrated with experimental motion data, showing similar motion results within 5 dB but with high-frequency discrepancies.

Watching Death in the Gerbil Cochlea Using Optical Coherence Tomography (OCT)

This study uses OCT to image the gerbil cochlea in vivo and postmortem, revealing changes in organ of Corti structures and fluid spaces during death.