Yun‐Gui Yang

This study creates a single-cell and spatially resolved atlas of human esophageal squamous cell carcinoma, identifying key tumor and fibroblast subgroups and their interactions in the tumor microenvironment.

This study identifies METTL1/WDR4-mediated m7G methylation of SCLT1 mRNA as a mechanism promoting gefitinib resistance in NSCLC.

STASCAN improves spatial transcriptomics resolution by combining gene expression and histology images, revealing finer cell structures across species and tissues.

The paper analyzes RNA-seq and whole genome sequencing data from SARS-CoV-2 infected cells to determine if the virus integrates into the host genome, finding no evidence of integration.

This study shows that m6A-mediated cell-cell communication is essential for planarian regeneration, as disrupting m6A methyltransferase leads to regeneration failure.

This study investigates 3D genome reorganization during mouse spermatogenesis, revealing dynamic changes in TADs, chromatin loops, and transcriptional regulation.