Ying Yang

This study develops a phage transposon sequencing (TnSeq) platform to identify essential genes in bacteriophages, finding ~110 fitness-conferring genes in a jumbo phage model.

STASCAN improves spatial transcriptomics resolution by combining gene expression and histology images, revealing finer cell structures across species and tissues.

The paper identifies 5-hydroxymethylcytosine (5hmC) modifications associated with diabetic nephropathy using cfDNA and machine learning.

The paper analyzes RNA-seq and whole genome sequencing data from SARS-CoV-2 infected cells to determine if the virus integrates into the host genome, finding no evidence of integration.

This study shows that m6A-mediated cell-cell communication is essential for planarian regeneration, as disrupting m6A methyltransferase leads to regeneration failure.

This study shows that Mettl3 and m6A modification influence liver metabolic disorders and insulin resistance in mice fed a high-fat diet.