Author

David Goldenberg

Pennsylvania State UniversityORCID 0000-0002-2822-4116Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

David Goldenberg1 paper · Penn State Milton S. Hershey Medical Center

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David Y. GoldrichiD· 2 shared James Riley BroachiD· 2 shared Alex R. HastieiD· 1 shared Andy Wing Chun PangiD· 1 shared Benjamin Clifford· 1 shared Brandon LaBarge· 1 shared Cesar A. AliagaiD· 1 shared Chi-Yu LaiiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

David Y. GoldrichORCID

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2 papers

Recent·Most cited

Genome Instability Precedes Viral Integration in Human Papilloma Virus Transformed Tonsillar Keratinocytes

Kimberly Chan, Christopher C. Tseng, Emily Milarachi, David Y. Goldrich, Lisa M. Schneper, Kathryn E. Sheldon, Samina Alam, Cesar A. Aliaga, Sreejata Chatterjee, Karam El‐Bayoumy, Craig Meyers, David Goldenberg, James Riley Broach

This study shows that genomic instability occurs before viral integration in HPV-transformed cells and that episomal virus leads to less tumorigenicity than integrated virus.

Molecular Cancer Research · Oct 30, 2024Peer-reviewedCancer Biology

Identification of Somatic Structural Variants in Solid Tumors By Optical Genome Mapping

David Y. Goldrich, Brandon LaBarge, Scott Chartrand, Lijun Zhang, Henry B. Sadowski, Yang Zhang, Khoa Pham, Hannah Way, Chi-Yu Lai, Andy Wing Chun Pang, Benjamin Clifford, Alex R. Hastie, Mark Oldakowski, David Goldenberg, James Riley Broach

This paper describes a method using optical genome mapping to identify somatic structural variants in solid tumors, showing high reliability and functional relevance.

Journal of Personalized Medicine · Feb 18, 2021Peer-reviewedGenetic & Genomic Medicine