Evolutionarily labile pachytene piRNAs target an altered set of mRNAs in male hybrids of house mouse subspecies
Martin Säflund, Masomeh Askari, Atiyeh Eghbali, Mukhtar Mohamed Abdi, John L. Fitzpatrick, Tianxiong Yu, Deniz Mahmut Özata
This study examines the evolutionary dynamics of pachytene piRNAs in mouse subspecies hybrids, showing that rapidly evolving piRNA genes can gain or lose mRNA targets in hybrids.
bioRxiv · Jul 8, 2026 · PreprintEvolutionary Biology