Thomas P. Sakmar

The paper develops a minimally invasive workflow to recover biological signatures from Renaissance-era artifacts, revealing microbial biomes and Y-chromosome markers linked to historical handling and conservation.

The paper compares sampling techniques for microbial DNA recovery from artworks on paper, finding wet vacuuming yields higher DNA recovery than other methods.

This paper describes a method to stabilize A{beta} protofibrils using an engineered chaperone-like protein, enabling the discovery of conformation-sensitive anti-A{beta} monoclonal antibodies that target protofibrils over monomers or plaques.