Molecular BiologybioRxivPreprint
ER oxidoreductin-1α and unfolded protein response as sex-dependent drivers of cardiorenal dysfunction in experimental autoimmune encephalomyelitis
Kayla L. Nguyen, Kelly Tammen, A.M. McDermott…·John R. Bethea
This study investigates sex-specific cardiorenal dysfunction in EAE, finding distinct ER stress/UPR alterations and sex-dependent therapeutic responses to ERO1 inhibition and IRE1 activation.
DOI 10.1101/2025.10.06.680703