Molecular BiologybioRxivPreprint
Nuclear Expression and DNA Binding Capacity of Receptor for Advanced Glycation End Products in Renal Tissue
Brooke E. Harcourt, Aaron McClelland, Hiroshi Yamamoto…·Josephine Maree Forbes
The paper identifies a nuclear RAGE isoform in kidney tissue that binds to its own gene promoter, suggesting self-regulation of RAGE expression, which is altered in obesity and kidney disease.