Author

Hideto Yonekura

Kanazawa Medical UniversityORCID 0000-0002-0010-1237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Aaron McClellandiD· 1 shared Aaron Thurman· 1 shared Abhiram Kunamneni· 1 shared Abraham Raskind· 1 shared Amelia K. FotheringhamiD· 1 shared Arya JoshiiD· 1 shared Brooke E. HarcourtiD· 1 shared David Alan VeseyiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Aaron McClellandORCID

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2 papers

Recent·Most cited

HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

Takayuki Ikeda, Sungki Hong, Shota Yoshida, Swayam Prakash Srivastava, Abhiram Kunamneni, Yao Yao, Om Khuperkar, Venkatesha Basrur, Henry Kuang, Maureen T. Kachman, Abraham Raskind, Heidi Baum, Arya Joshi, Vinamra Swaroop, Aaron Thurman, , Ken Inoki

This study shows HUWE1 enhances mTORC1 activity by promoting Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis via CAD activation.

Cell Reports · Oct 1, 2025Peer-reviewedBiochemistry

Nuclear Expression and DNA Binding Capacity of Receptor for Advanced Glycation End Products in Renal Tissue

Brooke E. Harcourt, Aaron McClelland, Hiroshi Yamamoto, Hideto Yonekura, Yasuhiko Yamamoto, Sally A. Penfold, Amelia K. Fotheringham, David Alan Vesey, David Wayne Johnson, Melinda T. Coughlan, Mark Emmanuel Cooper, Phillip Kantharidis, Josephine Maree Forbes

The paper identifies a nuclear RAGE isoform in kidney tissue that binds to its own gene promoter, suggesting self-regulation of RAGE expression, which is altered in obesity and kidney disease.

bioRxiv · May 9, 2019 · PreprintMolecular Biology