Tiechao Ruan

This study identifies DNAH3 variants in infertile men and shows that DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice.

This study identifies IQCH as a gene critical for male fertility, showing that its deficiency causes infertility in humans and mice through defects in sperm structure and function.

This study identifies CFAP52 mutations as a cause of male infertility with sperm head-tail connection and flagella defects in humans and mice, showing CFAP52's role in sperm development and potential as a diagnostic target.