Protein import-driven mitochondrial hyperactivation dictates angiogenesis independently of HIF-1α
Tanvi Chaudhary, Sharath Mohan Bhat, Priyadarshika Pradhan, Manjunath Bandu Joshi, Devanjan Sinha
The paper identifies a non-hypoxia-dependent mechanism of angiogenesis driven by mitochondrial hyperactivation via enhanced protein import, independent of HIF-1α.
bioRxiv · Apr 14, 2026 · PreprintCancer Biology