Heining Cham

This study shows that Egr1 overexpression induces sex-specific changes in neuronal chromatin, gene expression, and behavior in female rodents, mimicking high-oestrogenic phases and affecting hormone-depleted females.

This study identifies biomarkers in postmortem tissues to determine menopausal status, enabling research into MT-related brain disease risks.

The paper shows how early-life stress and ovarian hormones affect transcriptional regulation in the nucleus accumbens, leading to sex-specific responses to cocaine in mice.

This study investigates sex and estrous cycle effects on anxiety- and depression-related phenotypes in a two-hit developmental stress model, finding sex-specific impacts of early-life and adolescent stress.