Author

Laura Medina‐Ruiz

University of GlasgowORCID 0000-0002-2934-534XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Gerard J. GrahamiD· 3 shared Heather A. MathieiD· 3 shared Elise PitmoniD· 2 shared John ColeiD· 2 shared Marieke PingeniD· 2 shared Robin BartoliniiD· 2 shared Zuzanna Pocalun· 2 shared Ayumi FukuokaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

Gerard J. GrahamORCID

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Author profile →

4 papers

Recent·Most cited

Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity

Gillian J. Wilson, Lily Koumbas Foley, Zuzanna Pocalun, Elise Pitmon, Ayumi Fukuoka, Kit M. Lee, Lauren Fernandez, Heather A. Mathie, Robin Bartolini, Laura Medina‐Ruiz, John Cole, Gerard J. Graham

This study shows that ACKR2 regulates eosinophil levels in bone marrow, affecting monocyte differentiation and anti-bacterial immunity.

Nature Communications · Jul 22, 2026Peer-reviewedImmunology

Chemokine receptor expression defines a trajectory from monocytes to mature macrophages.

Heather A. Mathie, Laura Medina‐Ruiz, Fabian Schuette, Heba A. Halawa, Zuzanna Pocalun, Elise Pitmon, John Cole, Marieke Pingen, Gerard J. Graham

The paper shows that chemokine receptors in macrophages are non-redundant and change with differentiation and inflammatory stimuli.

bioRxiv · Oct 27, 2025 · PreprintImmunology

Biological context modulates virus-host dynamics and diversification

Rodrigo Sanchez-Martinez, Esther Rubio‐Portillo, Laura Medina‐Ruiz, Jonas Sarasa, María del Pilar Velásquez Enciso, Fernando Santos, Josefa Antón

This study shows that biological complexity affects virus-host dynamics by altering population-level lysis, mutation rates, and evolutionary trajectories.

bioRxiv · Sep 10, 2025 · PreprintMicrobiology

Inflammatory chemokine receptors CCR1, CCR2, CCR3 and CCR5 are essential for an optimal T cell response to influenza.

Marieke Pingen, Catherine E. Hughes, Laura Medina‐Ruiz, Heather A. Mathie, Jennifer A. Barrie, Chris A. H. Hansell, Robin Bartolini, Megan K. L. MacLeod, Gerard J. Graham

This study shows that CCR1/2/3/5 deletion reduces CD4 T cell responses but not CD8 T cell responses to influenza virus infection.

Mucosal Immunology · May 23, 2025Peer-reviewedImmunology